Alexandros D. Tselepis has graduated in Pharmacy from the University of Thessaloniki and in Medicine from the University of Ioannina. He obtained his PhD in Clinical Biochemistry in 1986 from the University of Ioannina, Greece. He continued his research studies as a Postdoctoral Fellow (Fogarty, NIH) at the University of Texas Health Science Center, at San Antonio, USA (1988–1989) as well as taking a sabbatical leave at INSERM U323, Paris (1994-1999, three months each year). After initial appointments as Assistant and Associate Professor, he took up his current position of Professor of Biochemistry–Clinical Chemistry in the University of Ioannina, in 2006. Professor Tselepis is also the Director of the Atherothrombosis Research Centre of the University of Ioannina. His main scientific interests are in the pathophysiology of Atherothrombosis. He has more than 263 publications at international journals and more than 8,000 citations, whereas his current h-index is 46 (Scopus).
Mailing Address: Thrombosis Research Laboratory, via Orus 2/B, 35129 Padova, Italy
Tel. +39 49 8212377 e-mail: vittorio.pengo@unipd.it
| M.D. degree | University of Padova 1974 |
| Residency | Internal Medicine, University of Padova |
| Certification | Internal Medicine 1980
Cardiology 1985 |
| Post Graduate training | Clinical Medicine 1974-1983
Research Fellow, Cardeza Foundation, Philadelphia, PA, USA 1984-1985 Visiting scientist, Cardeza Foundation, Philadelphia, PA, USA, 1988 Clinical Cardiology 1988- |
| Clinical Interests | Primary/secondary prevention and treatment of venous and arterial thromboembolism |
| Research Interests | Pathophysiology and treatment of thrombosis. |
| Professional activity | Professor of Cardiovascular Medicine, Department of Cardiac Thoracic and Vascular Sciences, and Director of Thrombosis Center, University of Padova School of Medicine, Padova Italy (1988-2019) |
| Senior Scientist | University of Padova and Arianna Foundation on Anticoagulation (2019-)
Reference Lab of APS action America (2014-) |
| Study awards - scholarships - grants | -Study Award on "Coagulation and Liver Diseases" arranged by the University of Padua. AA 1981-1982.
- Two-year scholarship (1984-1985) for studies on: "Calciparin and secondary prevention of heart attack" arranged by Italfarmaco SpA and accepted by the Institute of Clinical Medicine University of Padua. -Contribution from the Vittorio Tonolli Cultural Foundation for Cardiology for travel expenses to the USA for studies in the field of thrombosis. - Award of excellence in scientific research in the years 1996-2000 conferred by the University Scientific Commission (area 7). Department Booklet 'Scientific Activity 2000 page 69. |
| Scientific societies - associations - commissions | -Founder of the Italian Association of Anticoagulated Patients (AIPA) (1987)
-Chairman of the National Scientific Committee of the Federation of Associations of Patients on Treatment with Oral Anticoagulants (FEDER-AIPA) from 1995 to 2000. - Member of the steering committee of the Italian Society of Homostasis and Thrombosis (Siset) 1996 - Member of the editorial board of the journal 'Dialogue on drugs' (1999-2009). -Component of the European Forum for the study of antiphospholipid antibody syndrome -President of the Federation of Anticoagulated Surveillance Centers (FCSA) yrs 2000-2003 - Member of the working group of the Ministry of Health for the issuance of guidelines on therapy with oral anticoagulants. -Chairman of the Scientific Standardization Committee (SSC) on antiphospholipid antibodies 2007-2009 -President of the European and Mediterranean League against Thrombotic Diseases (EMLTD) 2016-2018 |
Reviwer for the following Journals:
New England Journal of Medicine, Circulation, Lancet, Blood, Journal of Thrombosis and Haemostasis, Thrombosis and Haemostasis, Thrombosis Research, American Journal of Cardiology, Haematologica, American Journal of Hematology, Journal of Cardiovascular Medicine, European Journal of Clinical Investigation, European Journal of Internal Medicine, Canadian Medical Association Journal
Associate Editor of Internal and Emergency Journal since 2011
Editorial Board member of Journal of Thrombosis and Haemostasis since 2003
Research activity
432 cited documents in International Journals (Scopus)
Total Citations: 20520, H-index: 68 (Scopus).
TWENTY MOST CITED PAPERS
1 Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism
Pengo, V., Lensing, A.W.A., Prins, M.H., (...), Iliceto, S., Prandoni, P. 2004
New England Journal of Medicine 350(22), pp. 2257-2264+2323
2
Bleeding complications of oral anticoagulant treatment: An inception-cohort, prospective collaborative study (ISCOAT) Palareti, G., Leali, N., Coccheri, S., (...), Berrettini, M., Musolesi, S. 1996 Lancet
348(9025), pp. 423-428
3
Update of the guidelines for lupus anticoagulant detection
Pengo, V., Tripodi, A., Reber, G., (...), Galli, M., De groot, P.G. 2009
Journal of Thrombosis and Haemostasis 7(10), pp. 1737-1740
4
D-dimer testing to determine the duration of anticoagulation therapy Palareti, G., Cosmi, B., Legnani, C., (...), Lensing, A.W.A., Tripodi, A. 2006
New England Journal of Medicine 355(17), pp. 1780-1789
5
The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients
Prandoni, P., Noventa, F., Ghirarduzzi, A., (...), Simioni, P., Pagnan, A. 2007
Haematologica 92(2), pp. 199-205+III-IV
6
The use of the dilute Russell viper venom time for the diagnosis of lupus anticoagulants Thiagarajan, P., Pengo, V., Shapiro, S.S. 1986
Blood 68(4), pp. 869-874
7
Chronic thromboembolic pulmonary hypertension
Kim, N.H., Delcroix, M., Jenkins, D.P., (...), Pengo, V., Mayer, E. 2013
Journal of the American College of Cardiology 62(25 SUPPL.), pp. D92-D99
8
Clinical course of high-risk patients diagnosed with antiphospholipid syndrome
Pengo, V., Ruffatti, A., Legnani, C., (...), Padayattil Jose, S., Iliceto, S. 2010
Journal of Thrombosis and Haemostasis 8(2), pp. 237-242
9
Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: Report of a Task Force at the 13th International Congress on Antiphospholipid Antibodies Ruiz-Irastorza, G., Cuadrado, M.J., Ruiz-Arruza, I., (...), Tektonidou, M., Khamashta, M. 2011
Lupus 20(2), pp. 206-218
10
PAIMS 2: Alteplase combined with heparin versus heparin in the treatment of acute pulmonary embolism. Plasminogen activator Italian multicenter study 2 Dalla-Volta, S., Palla, A., Santolicandro, A., (...), Marini, M.G., Visani, L. 1992
Journal of the American College of Cardiology 20(3), pp. 520-526
11
Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans Takahashi, H., Wilkinson, G.R., Nutescu, E.A., (...), Kijima, S., Echizen, H. 2006
Pharmacogenetics and Genomics 16(2), pp. 101-110
12
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance Scordo, M.G., Pengo, V., Spina, E., (...), Gusella, M., Padrini, R. 2002
Clinical Pharmacology and Therapeutics 72(6), pp. 702-710
13
Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: A multicenter prospective study
Pengo, V., Ruffatti, A., Legnani, C., (...), Jose, S.P., Iliceto, S. 2011
Blood 118(17), pp. 4714-4718
14
Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome
Pengo, V., Denas, G., Zoppellaro, G., (...), Gerosa, M., Banzato, A. 2018
Blood 132(13), pp. 1365-1371
15
The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: An international multicenter study
De Laat, B., Pengo, V., Pabinger, I., (...), Mertens, K., De Groot, P.G. 2009
Journal of Thrombosis and Haemostasis 7(11), pp. 1767-1773
16
Risk of recurrence after a first episode of symptomatic venous thromboembolism provoked by a transient risk factor: A systematic review
Open Access
Iorio, A., Kearon, C., Filippucci, E., (...), Siragusa, S., Palareti, G. 2010
Archives of Internal Medicine 170(19), pp. 1710-1716
17
A comparison of the safety and efficacy of oral antiocoagulation for the treatment of venous thromboembolic disease in patients with or without malignancy Palareti, G., Legnani, C., Lee, A., (...), Moia, M., Coccheri, S. 2000
Thrombosis and Haemostasis 84(5), pp. 805-810
18
Antibody profiles for the diagnosis of antiphospholipid syndrome Pengo, V., Biasiolo, A., Pegoraro, C., (...), Noventa, F., Iliceto, S. 2005
Thrombosis and Haemostasis 93(6), pp. 1147-1152
19
The risk for fatal pulmonary embolism after discontinuing anticoagulant therapy for venous thromboembolism Douketis, J.D., Gu, C.S., Schulman, S., (...), Pengo, V., Prandoni, P. 2007
Annals of Internal Medicine 147(11), pp. 766-774
20
EULAR recommendations for the management of antiphospholipid syndrome in adults
Tektonidou, M.G., Andreoli, L., Limper, M., (...), Tincani, A., Ward, M.M. 2019
Annals of the Rheumatic Diseases 78(10), pp. 1296-1304
Dr. Teresa Padro is a senior scientist and head of the research group on “Biomarkers for Cardiovascular Disease” in the Cardiovascular Program-ICCC at the Research Institute of the Hospital Santa Creu i Sant Pau (IR-HSCSP) in Barcelona (Spain). Previous positions included research scientist at the Münster-University (Medical School) in Germany and post-doctoral fellow at the Gaubius-Institute-TNO (Netherlands). Dr. Padro research interest focuses on vascular and cardiac disease pathology, coronary microcirculation, atherosclerosis, and thrombosis, with a research career oriented towards translational studies (from bench-to-bedside) aimed to identify new biomarkers or/and molecular targets with potential use in prevention, disease diagnosis, and treatment. Dr Padro expertise in the cardiovascular field is endorsed by more than 140 original articles and reviews (times-cited: 4,879; H-index: 36). Dr. Padro is General Secretary of the EMLTD since 2016 and Chairperson-Elect for the Working Group on Microcirculation and Coronary Pathophysiology (2020-2022) of the European Society of Cardiology.
Prof. Lina Badimon is the Director of the Cardiovascular Science Program (ICCC) at the Hospital Santa Creu and San Pau, Director of the Cardiovascular Research Chair of the Autonomous University of Barcelona, Professor at the National Research Council of Spain (CSIC), and Director of the UNESCO Chair in Biomedical Sciences Training and Research. She is Visiting Professor of Manchester Metropolitan University. Her research activities focus on cardio-metabolic diseases, thrombosis, atherosclerosis and ischemic heart disease. She has published over 570 articles in highly qualified scientific journals with her work highly quoted in the scientific literature (H-index: 84. Number of citations: >62,000. ORCID number: 0000-0002-9162-2459). She has written more of 250 reviews and book chapters.
He is Emeritus Professor of Hematology, Hadassah-Hebrew University Medical School. His areas of research include: Studying platelet function and interactions with vascular compartments under flow conditions, including testing the response to anti-platelet drugs and studying the role of platelets and platelet derived microparticles in angiogenesis and tumor biology.
Dr. Varon published over 130 original publications in leading journals as well as many chapters in textbooks in the field of hematology and vascular biology. He also holds several patents of the Cone and Plate(let) Analyzer –the CPA - a method and a system for testing platelet function under flow conditions.
Head of Cardiology Division; coordinator of Research Center; and adjunct of Clinical Director; Leiria Hospital Center
• Affiliated Professor, Oporto Medical School
• Member of the General Council, Polytechnic School of Leiria
• Integrated member of the Center for Innovative Care and Health Technology (CiTechCare)
• Advocacy Committee, European Society of Cardiology (ESC)
• Nucleus, Working Group Thrombosis (ESC), ex-officio member
• Executive Board and Councillor for Portugal, European Mediterranean League against Thrombotic Diseases (EMLTD)
• Author e co-author of more than 400 scientific papers, 156 published in “peer-review” journals (30318 citations; h-index 55)
• More than 500 scientific presentations by invitation, in Portugal and abroad
• Founder and chairman of the web educational platform “Challenges in Cardiology”
